Pempidine

Pempidine

SCHEMBL28985609

C=Cc1ccc(C(=O)O)cc1.CN1C(C)(C)CCCC1(C)C

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.49
CYP2C19 P33261 2/20 0.49
TSHR P16473 1/20 0.49
RARB P10826 13/20 0.43
RARG P13631 13/20 0.43
RARA P10276 12/20 0.43
RXRA P19793 5/20 0.40
ALDH1A1 P00352 3/20 0.40
POLB P06746 3/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CYP26A1 O43174 1/20 0.40
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29123138 0.79 RARB (0.40) NFKB1CYP2C19RARBRARGRARA
SCHEMBL16536 0.77 ALDH1A1 (0.62) TSHRALDH1A1POLBTP53SMN1; SMN2
SCHEMBL9742687 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2
SCHEMBL1059528 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2
SCHEMBL1886825 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2
Iodide SCHEMBL3628545 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2
SCHEMBL4344885 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2
SCHEMBL8490138 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2
Bromide SCHEMBL3627952 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2
SCHEMBL11050679 0.75 ALDH1A1 (0.60) TSHRALDH1A1POLBTP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115989217-A Composition, and optical material and lens using the same 三菱瓦斯化学株式会社 2023-04-18 CN disclosed