Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28986037 | 0.89 | RAB9A (0.58) | LMNAHTTPOLBALDH1A1NPC1 | |
| SCHEMBL28986044 | 0.88 | TAOK1 (0.48) | LMNAHTTSMN1; SMN2TP53NPC1 | |
| SCHEMBL28985992 | 0.87 | RAB9A (0.47) | LMNAHTTPOLBHPGDALDH1A1 | |
| SCHEMBL28986045 | 0.87 | KMT2A (0.47) | LMNAHTTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL28986036 | 0.86 | HDAC3 (0.48) | LMNAHTTSMN1; SMN2TP53NPC1 | |
| SCHEMBL28986053 | 0.85 | PPARG (0.49) | HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28986000 | 0.84 | TRPV1 (0.50) | LMNAHTTTP53NPC1RAB9A | |
| SCHEMBL28986008 | 0.83 | EPHX2 (0.50) | LMNAHTTSMN1; SMN2TP53NPC1 | |
| SCHEMBL28986005 | 0.83 | TRPV1 (0.53) | HTTNPC1RAB9A | |
| SCHEMBL28986055 | 0.82 | TRPV1 (0.52) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960047-B | 3-Phenyl-1H-pyrazole compound and application thereof | 中国药科大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-115960047-A | 3-phenyl-1H-pyrazole compound and application thereof | 中国药科大学 | 2023-04-14 | — | — | CN | disclosed |