Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739894 | 0.83 | CYP11B1 (0.44) | KDM4EMAPTMEN1KMT2AANPEP | |
| SCHEMBL6784220 | 0.83 | BRPF1 (0.37) | KDM4EMAPTMEN1KMT2AANPEP | |
| SCHEMBL12776571 | 0.77 | CYP2A6 (0.42) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1408720 | 0.75 | HPGD (0.51) | KDM4EMEN1KMT2AANPEPALDH1A1 | |
| SCHEMBL6740645 | 0.72 | ANPEP (0.38) | KDM4EMAPTMEN1KMT2AANPEP | |
| SCHEMBL6788345 | 0.72 | MAPT (0.36) | KDM4EMAPTMEN1KMT2APAX8 | |
| SCHEMBL12776616 | 0.70 | KDM4E (0.39) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13239543 | 0.69 | CYP1A2 (0.52) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2604372 | 0.69 | MAPT (0.41) | KDM4EMAPTMEN1KMT2APAX8 | |
| SCHEMBL30404908 | 0.68 | KMT2A (0.46) | MAPTMEN1KMT2AALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507212-B | Benzoindoline-dihydroquinolinone derivative fluorescent probe and preparation method and application thereof | 河南理工大学 | 2023-03-24 | — | — | CN | disclosed |