Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337214 | 1.00 | DYRK1A (0.50) | DYRK1APDK1DYRK3DYRK2GSK3B | |
| SCHEMBL28987624 | 0.86 | DYRK1A (0.43) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL30337437 | 0.86 | DYRK1A (0.43) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL28987589 | 0.85 | DYRK1A (0.42) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL30337440 | 0.85 | GSK3B (0.54) | DYRK1APDK1GSK3BCDK1CCNB1 | |
| SCHEMBL17490446 | 0.85 | GSK3B (0.54) | DYRK1APDK1GSK3BCDK1CCNB1 | |
| SCHEMBL30337352 | 0.85 | DYRK1A (0.42) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL28904600 | 0.84 | DYRK1A (0.68) | DYRK1APDK1DYRK3DYRK2GSK3B | |
| SCHEMBL28987580 | 0.84 | DYRK1A (0.41) | DYRK1APDK1GSK3BCDK1CCNB1 | |
| SCHEMBL30337183 | 0.84 | DYRK1A (0.41) | DYRK1APDK1GSK3BCDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |