Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 6/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987589 | 1.00 | DYRK1A (0.42) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL30337212 | 0.89 | DYRK1A (0.45) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL19254846 | 0.89 | DYRK1A (0.45) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL30337437 | 0.88 | DYRK1A (0.43) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL28987624 | 0.88 | DYRK1A (0.43) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL17490446 | 0.86 | GSK3B (0.54) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL30337440 | 0.86 | GSK3B (0.54) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL30337183 | 0.85 | DYRK1A (0.41) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL28987580 | 0.85 | DYRK1A (0.41) | DYRK1AGSK3BCDK1CCNB1DYRK1B | |
| SCHEMBL28987641 | 0.85 | DYRK1A (0.50) | DYRK1AGSK3BCDK1CCNB1DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-B | Preparation method of Ornitinib intermediate | 奥锐特药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |