Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.52 |
| ▸ | CDK7 | P50613 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337219 | 1.00 | MKNK1 (0.53) | MKNK1MKNK2GSK3BLCKIGF1R | |
| SCHEMBL17683243 | 0.90 | MKNK2 (0.53) | MKNK1MKNK2GSK3BLCKIGF1R | |
| SCHEMBL30337437 | 0.84 | DYRK1A (0.43) | MKNK1MKNK2GSK3BMAP3K14MEN1 | |
| SCHEMBL28987624 | 0.84 | DYRK1A (0.43) | MKNK1MKNK2GSK3BMAP3K14MEN1 | |
| SCHEMBL28987589 | 0.83 | DYRK1A (0.42) | MKNK1MKNK2GSK3BLCKIGF1R | |
| SCHEMBL17490446 | 0.83 | GSK3B (0.54) | MKNK1MKNK2GSK3BLCKIGF1R | |
| SCHEMBL30337352 | 0.83 | DYRK1A (0.42) | MKNK1MKNK2GSK3BLCKIGF1R | |
| SCHEMBL30337440 | 0.83 | GSK3B (0.54) | MKNK1MKNK2GSK3BLCKIGF1R | |
| SCHEMBL22509188 | 0.82 | GSK3B (0.49) | GSK3BLCKIGF1RGSK3ACDK7 | |
| SCHEMBL30705252 | 0.82 | GSK3B (0.49) | GSK3BLCKIGF1RGSK3ACDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |