Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 13/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30238994 | 0.89 | MAP3K5 (0.39) | MAP3K5NPC1RAB9A | |
| SCHEMBL28987786 | 0.86 | GRM5 (0.43) | MAP3K5NPC1RAB9AKMT2AGRM5 | |
| SCHEMBL28394631 | 0.85 | MAP3K5 (0.39) | MAP3K5MAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28388036 | 0.85 | DAO (0.40) | MAP3K5MAPTPOLBKDM4EKMT2A | |
| SCHEMBL28648131 | 0.74 | MAP3K5 (0.44) | MAP3K5 | |
| SCHEMBL28987774 | 0.74 | RBP4 (0.40) | MAP3K5KDM4EGRM5GRM1ALDH1A1 | |
| SCHEMBL28987769 | 0.74 | DAO (0.40) | MAP3K5MAPTKDM4EKMT2AGRM5 | |
| SCHEMBL20802893 | 0.73 | MAP3K5 (0.53) | MAP3K5MAP3K6 | |
| SCHEMBL15143877 | 0.72 | MAP3K5 (0.65) | MAP3K5MAP3K6 | |
| SCHEMBL28987778 | 0.72 | MAP3K5 (0.39) | MAP3K5POLBGRM5GRM1MAP3K6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294746-B | Novel ASK1 inhibitor and application thereof | 山东轩竹医药科技有限公司 | 2023-01-31 | — | — | CN | disclosed |