Sugi Predict

Sugi Predict / Compounds / Pyruvate

Pyruvate

Pyruvate

SCHEMBL28989557

CC(=O)C(=O)O.O=C(O)C(=O)CC(O)C(O)COP(=O)(O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PGD P52209 5/20 0.51
▸ PGK1 P00558 1/20 0.46
▸ PGK2 P07205 1/20 0.46
▸ MPI P34949 1/20 0.43
▸ LPAR6 P43657 1/20 0.34
▸ LPAR1 Q92633 1/20 0.34
▸ LPAR4 Q99677 1/20 0.34
▸ LPAR5 Q9H1C0 1/20 0.34
▸ LPAR2 Q9HBW0 1/20 0.34
▸ LPAR3 Q9UBY5 1/20 0.34
▸ ENPP2 Q13822 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL666269 0.93 PGD (0.58) PGDPGK1PGK2MPILPAR6
SCHEMBL23888257 0.93 PGD (0.58) PGDPGK1PGK2MPILPAR6
SCHEMBL30899166 0.93 PGD (0.58) PGDPGK1PGK2MPILPAR6
SCHEMBL12189551 0.93 PGD (0.58) PGDPGK1PGK2MPILPAR6
SCHEMBL321570 0.83 PGD (0.55) PGDPGK1PGK2MPILPAR6
SCHEMBL2619139 0.83 PGD (0.55) PGDPGK1PGK2MPILPAR6
SCHEMBL1972777 0.83 PGD (0.55) PGDPGK1PGK2MPILPAR6
SCHEMBL5791056 0.80 PGD (0.55) PGDPGK1PGK2MPILPAR6
SCHEMBL29550870 0.75 PGD (0.54) PGDPGK1PGK2MPI
SCHEMBL18341413 0.75 PGD (0.67) PGDPGK1PGK2MPILPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667518-A Recombinant microorganisms and methods 麦考瑞大学 2023-01-31 — — CN disclosed