Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012702 | 0.96 | BRD4 (0.39) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL28989548 | 0.92 | BRD4 (0.40) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL30242656 | 0.88 | BRD4 (0.41) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL24012476 | 0.88 | BRD4 (0.39) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL30242724 | 0.88 | BRD4 (0.39) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL24013067 | 0.88 | BRD4 (0.41) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL24012478 | 0.88 | BRD4 (0.39) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL30242692 | 0.88 | BRD4 (0.39) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL24013151 | 0.86 | BRD4 (0.41) | BRD4L3MBTL1MAPTPPARGPPARA | |
| SCHEMBL28989688 | 0.84 | BRD4 (0.41) | BRD4L3MBTL1MAPTPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996932-A | New macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2023-04-21 | — | — | CN | disclosed |