Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426839 | 0.76 | ALDH1A1 (0.52) | L3MBTL1KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL1895320 | 0.76 | CNR1 (0.61) | GAASMN1; SMN2L3MBTL1KMT2AMEN1 | |
| SCHEMBL10341777 | 0.72 | HSP90AA1 (0.85) | SMN1; SMN2TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL5909023 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL5909291 | 0.70 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL12332491 | 0.70 | SMN1; SMN2 (0.69) | GAASMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL3399685 | 0.70 | CNR1 (0.55) | GAASMN1; SMN2L3MBTL1KDM4EMAPT | |
| SCHEMBL5908986 | 0.70 | SMN1; SMN2 (1.00) | GAASMN1; SMN2TSHRL3MBTL1KMT2A | |
| SCHEMBL27607283 | 0.70 | AKR1C3 (0.83) | GAASMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL16026460 | 0.70 | CA12 (0.71) | GAASMN1; SMN2TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |