SCHEMBL28990488

SCHEMBL28990488

COCOCCCC(OC(N)=O)c1c(Cl)cccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.33
APP P05067 1/20 0.32
GLA P06280 1/20 0.32
ADRB1 P08588 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2B P41595 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28990617 1.00 HPGD (0.33) HPGDAPPGLAADRB1HTR2A
SCHEMBL28990759 1.00 HPGD (0.33) HPGDAPPGLAADRB1HTR2A
SCHEMBL28990709 0.92 HPGD (0.33) HPGDGLAADRB1HTR2AHTR2B
SCHEMBL28990544 0.92 HPGD (0.33) HPGDGLAADRB1HTR2AHTR2B
SCHEMBL28990789 0.90 HPGD (0.40) HPGDGLAP2RX7
SCHEMBL28990782 0.86 AVPR2 (0.35)
SCHEMBL28990727 0.86 AVPR2 (0.35)
SCHEMBL28990700 0.84 HPGD (0.38) HPGDGLAADRB1HTR2AHTR2B
SCHEMBL19254688 0.80 KMT2A (0.38) HPGD
SCHEMBL18567606 0.80 KMT2A (0.38) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN claimed
CN-111419830-B Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes 比皮艾思药物研发有限公司 2024-01-30 CN disclosed
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN disclosed