Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990700 | 0.92 | HPGD (0.38) | HPGDGLAALDH1A1TSHRP2RX7 | |
| SCHEMBL28990488 | 0.90 | HPGD (0.33) | HPGDGLAP2RX7 | |
| SCHEMBL28990617 | 0.90 | HPGD (0.33) | HPGDGLAP2RX7 | |
| SCHEMBL28990759 | 0.90 | HPGD (0.33) | HPGDGLAP2RX7 | |
| SCHEMBL28990639 | 0.85 | HPGD (0.37) | HPGDGLAALDH1A1TSHRP2RX7 | |
| SCHEMBL28990797 | 0.85 | HPGD (0.37) | HPGDGLAALDH1A1TSHRP2RX7 | |
| SCHEMBL19254688 | 0.84 | KMT2A (0.38) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL18567606 | 0.84 | KMT2A (0.38) | HPGDALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL28990544 | 0.84 | HPGD (0.33) | HPGDGLAP2RX7 | |
| SCHEMBL28990709 | 0.84 | HPGD (0.33) | HPGDGLAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |