Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990596 | 1.00 | AVPR2 (0.35) | AVPR2AVPR1ACASP1AOC3ATM | |
| SCHEMBL28990603 | 1.00 | AVPR2 (0.35) | AVPR2AVPR1ACASP1AOC3ATM | |
| SCHEMBL28990727 | 0.93 | AVPR2 (0.35) | AVPR2AVPR1ACASP1AOC3ATM | |
| SCHEMBL28990782 | 0.93 | AVPR2 (0.35) | AVPR2AVPR1ACASP1AOC3ATM | |
| SCHEMBL28990550 | 0.90 | CYP1A2 (0.37) | AVPR2AVPR1AP2RX7 | |
| SCHEMBL28990758 | 0.90 | CYP1A2 (0.37) | AVPR2AVPR1AP2RX7 | |
| SCHEMBL28990667 | 0.89 | CASP1 (0.38) | AVPR2AVPR1ACASP1AOC3ATM | |
| SCHEMBL28990632 | 0.89 | CASP1 (0.38) | AVPR2AVPR1ACASP1AOC3ATM | |
| SCHEMBL28990781 | 0.87 | AVPR2 (0.36) | AVPR2AVPR1ACASP1AOC3ATM | |
| SCHEMBL28990544 | 0.86 | HPGD (0.33) | ADRB1HTR2AHTR2BSIGMAR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |