Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 3/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 4/20 | 0.46 |
| ▸ | SNCA | P37840 | 3/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386339 | 1.00 | STING1 (0.52) | STING1CHRNA7IGF1RSNCATMPRSS4 | |
| SCHEMBL30387511 | 0.89 | SNCA (0.51) | STING1CHRNA7SNCAGRIK1 | |
| SCHEMBL28991293 | 0.89 | SNCA (0.51) | STING1CHRNA7SNCAGRIK1 | |
| SCHEMBL30885411 | 0.86 | STING1 (0.70) | STING1SNCATMPRSS4GRIK1NTRK1 | |
| SCHEMBL30387362 | 0.81 | STING1 (0.62) | STING1SNCATMPRSS4GRIK1BRAF | |
| SCHEMBL28991278 | 0.81 | STING1 (0.62) | STING1SNCATMPRSS4GRIK1BRAF | |
| SCHEMBL23207649 | 0.78 | STING1 (0.65) | STING1GRIK1 | |
| SCHEMBL29307516 | 0.76 | F7 (0.51) | STING1F7F3 | |
| SCHEMBL22049870 | 0.76 | P2RY1 (0.49) | STING1IGF1RBRAF | |
| SCHEMBL22803837 | 0.76 | STING1 (0.77) | STING1GRIK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |