Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 8/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387362 | 1.00 | STING1 (0.62) | STING1GRIK1EPHX2KDRTEK | |
| SCHEMBL30885411 | 0.94 | STING1 (0.70) | STING1GRIK1EPHX2SNCAGOT1 | |
| SCHEMBL30387344 | 0.87 | STING1 (0.64) | STING1EPHX2GOT1 | |
| SCHEMBL28991900 | 0.87 | STING1 (0.64) | STING1EPHX2GOT1 | |
| SCHEMBL28991301 | 0.86 | STING1 (0.57) | STING1GRIK1NHERF1 | |
| SCHEMBL30387111 | 0.86 | STING1 (0.57) | STING1GRIK1NHERF1 | |
| SCHEMBL23207649 | 0.85 | STING1 (0.65) | STING1GRIK1EPHX2GOT1 | |
| SCHEMBL22803837 | 0.84 | STING1 (0.77) | STING1GRIK1EPHX2GOT1MTOR | |
| SCHEMBL30387083 | 0.82 | STING1 (0.56) | STING1GRIK1SNCAGOT1NHERF1 | |
| SCHEMBL28991333 | 0.82 | STING1 (0.56) | STING1GRIK1SNCAGOT1NHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |