Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387020 | 1.00 | STING1 (0.61) | STING1TRPV1EPHX2IGF1RNHERF1 | |
| SCHEMBL30885398 | 0.92 | STING1 (0.72) | STING1TRPV1EPHX2IGF1RGOT1 | |
| SCHEMBL30387344 | 0.87 | STING1 (0.64) | STING1TRPV1EPHX2IGF1RGOT1 | |
| SCHEMBL28991251 | 0.87 | STING1 (0.64) | STING1TRPV1EPHX2IGF1RNHERF1 | |
| SCHEMBL30387260 | 0.87 | STING1 (0.64) | STING1TRPV1EPHX2IGF1RNHERF1 | |
| SCHEMBL28991900 | 0.87 | STING1 (0.64) | STING1TRPV1EPHX2IGF1RGOT1 | |
| SCHEMBL30885411 | 0.84 | STING1 (0.70) | STING1EPHX2NHERF1GOT1GRIK1 | |
| SCHEMBL28991235 | 0.83 | STING1 (0.72) | STING1NHERF1GRIK1 | |
| SCHEMBL30387235 | 0.83 | STING1 (0.72) | STING1NHERF1GRIK1 | |
| SCHEMBL30885397 | 0.83 | STING1 (0.51) | STING1NHERF1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |