Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 6/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | GOT1 | P17174 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.48 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 3/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387260 | 1.00 | STING1 (0.64) | STING1TRPV1EPHX2GOT1IGF1R | |
| SCHEMBL30885398 | 0.94 | STING1 (0.72) | STING1TRPV1EPHX2GOT1IGF1R | |
| SCHEMBL28991900 | 0.88 | STING1 (0.64) | STING1TRPV1EPHX2GOT1IGF1R | |
| SCHEMBL30387344 | 0.88 | STING1 (0.64) | STING1TRPV1EPHX2GOT1IGF1R | |
| SCHEMBL30387020 | 0.87 | STING1 (0.61) | STING1TRPV1EPHX2GOT1IGF1R | |
| SCHEMBL28991890 | 0.87 | STING1 (0.61) | STING1TRPV1EPHX2GOT1IGF1R | |
| SCHEMBL30885459 | 0.84 | STING1 (0.51) | STING1NHERF1SNCA | |
| SCHEMBL28991333 | 0.82 | STING1 (0.56) | STING1TRPV1GOT1NHERF1SNCA | |
| SCHEMBL30387083 | 0.82 | STING1 (0.56) | STING1TRPV1GOT1NHERF1SNCA | |
| SCHEMBL30386562 | 0.81 | STING1 (0.53) | STING1TRPV1EPHX2IGF1RP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023321-A | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2023-04-28 | — | — | CN | disclosed |