Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.54 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.54 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23987190 | 0.81 | APP (0.63) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL12244543 | 0.80 | APP (0.56) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL29939792 | 0.77 | APP (0.87) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL10535194 | 0.77 | APP (0.87) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL23987113 | 0.77 | ALOX5 (0.59) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL10536246 | 0.77 | ALOX5 (0.66) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL21710551 | 0.74 | PTPN1 (0.64) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL21426166 | 0.74 | PTPN1 (0.88) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL29467209 | 0.74 | PTPN1 (0.88) | APPSLC6A2TRPA1LDHACNR1 | |
| SCHEMBL29777969 | 0.74 | PTPN1 (0.66) | APPSLC6A2TRPA1LDHACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116036080-B | Application of pyranopyridone compounds in preparation of medicines for treating liver cancer | 江西省林业科学院 | 2023-06-06 | — | — | CN | disclosed |
| CN-116036080-A | Application of pyranopyridone compounds in preparation of medicines for treating liver cancer | 江西省林业科学院 | 2023-05-02 | — | — | CN | disclosed |