SCHEMBL28992489

SCHEMBL28992489

C=CC(=O)OC(=O)C#CC

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.34
HPGD P15428 1/20 0.33
ALDH1A1 P00352 5/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779353 0.77 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL29039919 0.72 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL29451229 0.71
SCHEMBL14052652 0.71
SCHEMBL278164 0.71
Acetic Acid SCHEMBL25407380 0.70 FFAR3 (0.39) TSHRALDH1A1
SCHEMBL775881 0.70
SCHEMBL28914240 0.69
SCHEMBL7076062 0.68 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5071464 0.68 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116057036-A Fluorine-containing carboxylate compound 大金工业株式会社 2023-05-02 CN disclosed