Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230208 | 1.00 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7665294 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL30257239 | 0.87 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL28992949 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL30230074 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL13643404 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL28992940 | 0.82 | KDM4E (0.72) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL30230250 | 0.82 | KDM4E (0.72) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL2356937 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL28992907 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872939-A | 2,3-dihydroquinazoline-4 (1H) -ketone derivative and preparation and application thereof | 武汉科技大学 | 2023-03-31 | — | — | CN | disclosed |