Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28993019 | 0.75 | MPO (0.34) | MPONLRP3CCNT1CDK9 | |
| SCHEMBL19431919 | 0.73 | MPO (0.42) | MPONLRP3CCNT1CDK9MAPK14 | |
| SCHEMBL20939452 | 0.73 | MPO (0.42) | MPONLRP3CCNT1CDK9MAPK14 | |
| SCHEMBL2054538 | 0.73 | MPO (0.42) | MPONLRP3CCNT1CDK9MAPK14 | |
| SCHEMBL18338520 | 0.73 | MPO (0.42) | MPONLRP3CCNT1CDK9MAPK14 | |
| Hydrochloric Acid SCHEMBL26120934 | 0.71 | MPO (0.41) | MPONLRP3CCNT1CDK9MAPK14 | |
| SCHEMBL26688638 | 0.70 | MPO (0.40) | MPONLRP3CCNT1CDK9MAPK14 | |
| SCHEMBL30431300 | 0.70 | MPO (0.40) | MPONLRP3MAPK14HDAC1HDAC8 | |
| SCHEMBL18418855 | 0.69 | MPO (0.39) | MPONLRP3CCNT1CDK9MAPK14 | |
| SCHEMBL21672110 | 0.69 | MPO (0.39) | MPONLRP3CCNT1CDK9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873000-B | Isoquinolinones and quinazolinones compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115873000-A | Isoquinolone and quinazolinone compounds, and composition and application thereof | 中山医诺维申新药研发有限公司 | 2023-03-31 | — | — | CN | disclosed |