Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 5/20 | 0.51 |
| ▸ | RXRA | P19793 | 5/20 | 0.45 |
| ▸ | RXRB | P28702 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289685 | 1.00 | NR4A2 (0.51) | NR4A2RXRARXRBNPC1POLB | |
| SCHEMBL28994247 | 0.89 | BTK (0.44) | NR4A2NPC1RAB9ABTKPPARG | |
| SCHEMBL30289606 | 0.89 | PARP10 (0.52) | BTKKMT2A | |
| SCHEMBL30289690 | 0.89 | BTK (0.44) | NR4A2NPC1RAB9ABTKPPARG | |
| SCHEMBL28994191 | 0.88 | MRGPRX4 (0.47) | NPC1RAB9ASMN1; SMN2BTKMEN1 | |
| SCHEMBL16748844 | 0.83 | BTK (0.47) | BTK | |
| SCHEMBL18900705 | 0.77 | BTK (0.43) | RAB9ABTKMEN1KMT2A | |
| SCHEMBL16748845 | 0.75 | DGAT1 (0.44) | BTK | |
| SCHEMBL15613577 | 0.75 | CYP4F2 (0.40) | BTKMRGPRX4 | |
| SCHEMBL2659482 | 0.74 | KMT2A (0.73) | NR4A2NR4A1NR4A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894497-A | Imidazopyrimidine compounds, and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |