Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | KDM6B | O15054 | 2/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15938666 | 0.79 | HDAC3 (0.66) | TERTHDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL10206277 | 0.78 | CA1 (0.46) | HDAC3HDAC1KDM6BKDM4DKDM4C | |
| SCHEMBL30079180 | 0.77 | HDAC1 (0.45) | HDAC3HDAC1KDM6BKDM4DKDM4C | |
| SCHEMBL7653834 | 0.77 | HDAC1 (0.45) | HDAC3HDAC1KDM6BKDM4DKDM4C | |
| SCHEMBL18858136 | 0.76 | MAPK8 (0.39) | HDAC3HDAC1KDM6BKDM4DKDM4C | |
| SCHEMBL27200474 | 0.76 | TERT (0.44) | TERTKDM6BKDM4DKDM4CEGLN3 | |
| SCHEMBL14357917 | 0.75 | HDAC1 (0.46) | HDAC3HDAC1KDM6BKDM4DKDM4C | |
| SCHEMBL27147974 | 0.74 | KDM4C (0.43) | HDAC3HDAC1KDM6BKDM4DKDM4C | |
| Hydrochloric Acid SCHEMBL29373586 | 0.73 | HDAC1 (0.45) | HDAC3HDAC1KDM6BKDM4DKDM4C | |
| Hydrochloric Acid SCHEMBL5749683 | 0.73 | HDAC1 (0.45) | HDAC3HDAC1KDM6BKDM4DKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182323-A1 | PYRIDO OXAZINE AMINO DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-05-24 | — | — | EP | disclosed |
| CN-116075307-A | Pyridooxazine amino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |