SCHEMBL28994863

SCHEMBL28994863

Cc1ccc(OCC[C@H]2CCN(C(=O)OC(C)(C)C)C2)cc1

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 12/20 0.60
CHEK2 O96017 1/20 0.51
CSF1R P07333 1/20 0.48
KDR P35968 1/20 0.48
KMT2A Q03164 1/20 0.47
TEAD1 P28347 1/20 0.47
TEAD3 Q99594 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28994953 1.00 GPR119 (0.60) GPR119CHEK2CSF1RKDRKMT2A
SCHEMBL13335340 0.84 GPR119 (0.70) GPR119CHEK2
SCHEMBL4159824 0.83 GPR119 (0.65) GPR119CHEK2
SCHEMBL2460337 0.83 GPR119 (0.65) GPR119CHEK2
SCHEMBL4322579 0.83 GPR119 (0.65) GPR119CHEK2KMT2A
SCHEMBL31269794 0.83 GPR119 (0.51) GPR119CHEK2CSF1RKDR
SCHEMBL25315425 0.83 GPR119 (0.54) GPR119KMT2A
SCHEMBL16415290 0.83 GPR119 (0.54) GPR119KMT2A
SCHEMBL19336726 0.83 GPR119 (0.48) GPR119CSF1RKDRKMT2A
SCHEMBL944213 0.83 GPR119 (0.62) GPR119CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116075309-A Vitamin D derivatives having cyclic amine in side chain 帝人制药株式会社 2023-05-05 CN disclosed