Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363732 | 0.84 | MEN1 (0.89) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL22820075 | 0.84 | HTT (0.61) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL27493749 | 0.83 | MEN1 (0.77) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL30739691 | 0.83 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL28994974 | 0.81 | HPGD (0.74) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL9343198 | 0.81 | KMT2A (0.66) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL27471728 | 0.80 | MEN1 (0.74) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL28995013 | 0.80 | MEN1 (0.62) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL22819966 | 0.79 | ALDH1A1 (0.70) | KMT2AMEN1NPC1RAB9ATDP1 | |
| SCHEMBL14825062 | 0.78 | NPC1 (1.00) | KMT2AMEN1NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890856-B | Method for synthesizing 2,2' -biphenyl-1-carboxylic acid derivative | 华南理工大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-114890856-A | Method for synthesizing 2,2' -biphenyl-1-carboxylic acid derivative | 华南理工大学 | 2022-08-12 | — | — | CN | disclosed |