SCHEMBL28995474

SCHEMBL28995474

Nc1cc(F)c(N2CCC(CCC(=O)O)CC2)c(F)c1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27098837 0.82 FFAR4 (0.41) FFAR4
SCHEMBL28995471 0.82 FFAR4 (0.53) FFAR4
SCHEMBL25031021 0.79 FFAR4 (0.40) FFAR4
SCHEMBL28855647 0.76 FFAR4 (0.38) FFAR4
SCHEMBL25194061 0.76 FFAR4 (0.39) FFAR4
SCHEMBL19510779 0.76 FFAR4 (0.47) FFAR4
SCHEMBL23551877 0.76 FFAR4 (0.48) FFAR4
SCHEMBL15651683 0.75 GFER (0.46) FFAR4
SCHEMBL242034 0.75 SLC18A3 (0.47) FFAR4
SCHEMBL1750804 0.75 FFAR4 (0.41) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901277-A Isoindolinone and indazole compounds for EGFR degradation C4医药公司 2022-08-12 — — CN disclosed
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