Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749218 | 0.84 | ALDH1A1 (0.44) | — | |
| SCHEMBL1749217 | 0.84 | ALDH1A1 (0.44) | — | |
| SCHEMBL1749215 | 0.84 | ALDH1A1 (0.44) | — | |
| SCHEMBL1750146 | 0.80 | RPS6KB1 (0.40) | ADORA2A | |
| SCHEMBL1749373 | 0.79 | MAPT (0.44) | — | |
| SCHEMBL1749371 | 0.79 | MAPT (0.44) | — | |
| SCHEMBL19510840 | 0.79 | FFAR4 (0.49) | FFAR4 | |
| SCHEMBL19510841 | 0.79 | FFAR4 (0.49) | FFAR4 | |
| SCHEMBL1749694 | 0.77 | MAPT (0.52) | — | |
| SCHEMBL1749697 | 0.77 | MAPT (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220191-A1 | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220191-A1 | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments | CYP11B2, CYP11B1, CYP1A1 | FFAR4 1785/4885ADORA2A 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.