Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CPN1 | P15169 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674085 | 0.96 | EPHX1 (0.47) | EPHX1CA1CA2SMN1; SMN2CPN1 | |
| SCHEMBL4281689 | 0.94 | EPHX1 (0.50) | EPHX1SMN1; SMN2 | |
| SCHEMBL4188387 | 0.92 | CA1 (0.38) | EPHX1CA1CA2SMN1; SMN2CPN1 | |
| SCHEMBL1478217 | 0.85 | CA1 (0.46) | EPHX1CA1CA2METAP1DPP4 | |
| SCHEMBL1478219 | 0.85 | CA1 (0.46) | EPHX1CA1CA2METAP1DPP4 | |
| SCHEMBL931251 | 0.83 | EPHX1 (0.47) | EPHX1CA1CA2METAP1DPP4 | |
| SCHEMBL4537552 | 0.82 | LCK (0.42) | EPHX1 | |
| SCHEMBL11010077 | 0.80 | EPHX1 (0.44) | EPHX1 | |
| SCHEMBL27719303 | 0.80 | EPHX1 (0.44) | EPHX1 | |
| SCHEMBL9245067 | 0.80 | CA2 (0.48) | EPHX1CA1CA2CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867133-A | Histone acetylation modulators for the treatment and prevention of organ injury | 密歇根大学董事会 | 2023-03-28 | — | — | CN | disclosed |