Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15159431 | 0.81 | NPC1 (0.52) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL30390480 | 0.78 | NPY5R (0.45) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL17048070 | 0.72 | NPC1 (0.54) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL16609509 | 0.72 | NPC1 (0.50) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL16609461 | 0.72 | NPY5R (0.44) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL16599521 | 0.72 | NPY5R (0.44) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL16599668 | 0.72 | NPC1 (0.50) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL28995798 | 0.72 | SMN1; SMN2 (0.49) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL30490193 | 0.71 | NPC1 (0.45) | NPC1RAB9AMAPTKDM4EGFER | |
| SCHEMBL7033840 | 0.71 | MAPT (0.63) | NPC1RAB9AMAPTKDM4EGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |