Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914270 | 0.80 | MAPT (0.44) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL8982 | 0.74 | TYMS (0.49) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL13041691 | 0.74 | ALDH1A1 (0.59) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL30065191 | 0.74 | MAPT (0.50) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL28394278 | 0.74 | MAPT (0.50) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL12213872 | 0.72 | MAPT (0.68) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL24625406 | 0.72 | KDM4E (0.53) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL7214734 | 0.72 | HSP90AA1 (0.51) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL18288212 | 0.71 | MAPT (0.47) | SMN1; SMN2POLBMAPTKDM4EHPGD | |
| SCHEMBL26423018 | 0.71 | CYP2A6 (0.41) | SMN1; SMN2MAPTKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |