Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 10/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | EZH1 | Q92800 | 10/20 | 0.51 |
| ▸ | EED | O75530 | 4/20 | 0.51 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.51 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.51 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.51 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.51 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.49 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995941 | 0.93 | EZH2 (0.67) | EZH2HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL28996081 | 0.92 | EZH2 (0.55) | EZH2HDAC1HDAC6EZH1EED | |
| SCHEMBL28996056 | 0.91 | EZH2 (0.61) | EZH2HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL28996011 | 0.89 | EZH2 (0.56) | EZH2HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL28996007 | 0.88 | EZH2 (0.67) | EZH2HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL28995933 | 0.88 | EZH2 (0.58) | EZH2HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL28996183 | 0.87 | EZH2 (0.71) | EZH2HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL28995932 | 0.85 | EZH2 (0.69) | EZH2HDAC1HDAC6EZH1EED | |
| SCHEMBL28996004 | 0.85 | EZH2 (0.65) | EZH2HDAC1HDAC6HDAC4HDAC7 | |
| SCHEMBL28996059 | 0.84 | EZH2 (0.68) | EZH2HDAC1HDAC6HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082320-A | ZESTE enhancer homolog 2 inhibitors and uses thereof | 海思科医药集团股份有限公司 | 2023-05-09 | — | — | CN | disclosed |