Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890772 | 0.85 | CTSC (0.74) | CTSCCTSK | |
| SCHEMBL2890767 | 0.85 | CTSC (0.74) | CTSCCTSK | |
| SCHEMBL16478355 | 0.84 | CTSC (0.38) | CTSCCTSK | |
| SCHEMBL16478360 | 0.82 | CTSC (0.50) | CTSCCTSK | |
| SCHEMBL16485760 | 0.79 | CTSC (0.62) | CTSCCTSK | |
| SCHEMBL2885213 | 0.79 | CTSC (0.54) | CTSCCTSK | |
| SCHEMBL2885215 | 0.79 | CTSC (0.54) | CTSCCTSK | |
| SCHEMBL289965 | 0.77 | CTSC (0.39) | CTSCCTSK | |
| SCHEMBL2891136 | 0.77 | CTSC (0.51) | CTSCCTSK | |
| SCHEMBL289370 | 0.76 | CTSC (0.72) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | claimed |
| EP-2427445-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | AstraZeneca AB (SE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |