Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369433 | 1.00 | EGFR (0.49) | EGFRKDRTEKEPHB4ALDH1A1 | |
| SCHEMBL30356990 | 1.00 | EGFR (0.49) | EGFRKDRTEKEPHB4ALDH1A1 | |
| SCHEMBL30357001 | 1.00 | EGFR (0.49) | EGFRKDRTEKEPHB4ALDH1A1 | |
| SCHEMBL26126243 | 1.00 | EGFR (0.49) | EGFRKDRTEKEPHB4ALDH1A1 | |
| SCHEMBL28996943 | 1.00 | EGFR (0.49) | EGFRKDRTEKEPHB4ALDH1A1 | |
| SCHEMBL25415602 | 0.93 | EGFR (0.48) | EGFRKDRTEKEPHB4ALDH1A1 | |
| SCHEMBL29370856 | 0.93 | EGFR (0.48) | EGFRKDRTEKEPHB4ALDH1A1 | |
| SCHEMBL28997013 | 0.90 | TGM2 (0.56) | EGFRKDRTEKEPHB4TGM2 | |
| SCHEMBL28996924 | 0.90 | TGM2 (0.56) | EGFRKDRTEKEPHB4TGM2 | |
| SCHEMBL25414485 | 0.90 | TGM2 (0.56) | EGFRKDRTEKEPHB4TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |