Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | APOB | P04114 | 2/20 | 0.38 |
| ▸ | MTTP | P55157 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997537 | 0.94 | TGM2 (0.53) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL28996914 | 0.94 | TGM2 (0.53) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL26124319 | 0.94 | TGM2 (0.53) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL29367058 | 0.90 | TGM2 (0.45) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL28996909 | 0.90 | TGM2 (0.45) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL28997000 | 0.90 | TGM2 (0.45) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL30356984 | 0.90 | TGM2 (0.45) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL30356987 | 0.90 | TGM2 (0.45) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL28996922 | 0.90 | TGM2 (0.45) | TGM2TEAD1FFAR1BRAFKDR | |
| SCHEMBL28997005 | 0.85 | TGM2 (0.44) | TGM2FFAR1BRAFKDRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-B | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2024-10-18 | — | — | CN | disclosed |
| EP-4188907-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2023-06-07 | — | — | EP | disclosed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022023460-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2022-02-03 | — | — | WO | disclosed |