Toluene

Toluene

SCHEMBL289971

C(OCC1CO1)C1CO1.Cc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.55
ALDH1A1 P00352 4/20 0.55
GLA P06280 1/20 0.55
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
TSHR P16473 6/20 0.44
TP53 P04637 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HIF1A Q16665 2/20 0.44
CYP3A4 P08684 1/20 0.44
LMNA P02545 1/20 0.44
ALOX12 P18054 1/20 0.44
ACHE P22303 1/20 0.44
MAPK1 P28482 1/20 0.44
MGLL Q99685 2/20 0.41
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
CYP1A2 P05177 1/20 0.40
PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL9388822 1.00 TDP1 (0.55) TDP1ALDH1A1GLAMEN1KMT2A
Toluene SCHEMBL9571021 1.00 TDP1 (0.55) TDP1ALDH1A1GLAMEN1KMT2A
Toluene SCHEMBL28119644 1.00 TDP1 (0.55) TDP1ALDH1A1GLAMEN1KMT2A
Toluene SCHEMBL28363945 0.92 TDP1 (0.52) TDP1ALDH1A1GLAMEN1KMT2A
Toluene SCHEMBL27659827 0.91 ALDH1A1 (0.47) TDP1ALDH1A1GLAMEN1KMT2A
P-Xylene SCHEMBL11836467 0.90 ALDH1A1 (0.50) TDP1ALDH1A1GLAMEN1KMT2A
SCHEMBL28093238 0.89 ALDH1A1 (0.49) TDP1ALDH1A1GLAMEN1KMT2A
1,6-Hexanediol SCHEMBL28539762 0.88 ALDH1A1 (0.45) TDP1ALDH1A1GLAMEN1KMT2A
O-Xylene SCHEMBL27476227 0.88 ALDH1A1 (0.63) TDP1ALDH1A1GLAMEN1KMT2A
M-Xylene SCHEMBL11844722 0.86 ALDH1A1 (0.52) TDP1ALDH1A1GLAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 815 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598752-A1 RUBBER COMPOSITION BASED ON PYROLYSIS CARBON BLACK AND EPOXY RESIN COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2025-08-13 EP claimed
CN-120192512-A Biological multi-functionality epoxy resin and epoxy adhesive, and preparation method and application thereof 韦尔通科技股份有限公司 2025-06-24 CN claimed
CN-119979080-A Yellowing-resistant epoxy resin adhesive and preparation method thereof 云胜电子胶粘剂(深圳)有限公司 2025-05-13 CN claimed
CN-119955434-A UV (ultraviolet) double-solid adhesive composition, and use method and preparation method thereof 南京诺邦新材料有限公司 2025-05-09 CN claimed
CN-119912851-A Preparation and application methods of antistatic wave-transparent coating for unmanned aerial vehicle radar cover 烟台先进材料与绿色制造山东省实验室 2025-05-02 CN claimed
CN-119775720-A Foaming putty for filling gaps of sandwich composite material and preparation method thereof 武汉航天智能防护科技有限责任公司 2025-04-08 CN claimed
CN-119752277-A High-resistance anti-corona paint, preparation method thereof and insulation structure 苏州巨峰电气绝缘系统股份有限公司 2025-04-04 CN claimed
CN-118981144-B Optical curtain with mildew-proof effect and manufacturing process thereof 东莞市晶致光学薄膜有限公司 2025-04-01 CN claimed
CN-119463047-A Alkali-soluble polyurethane acrylate resin and preparation method and application thereof 广东三求光固材料股份有限公司 2025-02-18 CN claimed
CN-119465776-A Semi-rigid and semi-flexible light steel bridge deck pavement structure and pavement method thereof 江苏中路工程技术研究院有限公司 2025-02-18 CN claimed
CN-102533060-A Solvent-free type fiber reinforced epoxy paint and preparation method thereof JIANGSU DAZHONG PAINT CO LTD 2012-07-04 CN claimed
US-20040186123-A1 Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline WYETH 2004-09-23 US claimed
US-6693197-B2 Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino- [2,3-f] quinoline WYETH 2004-02-17 US claimed
EP-1387845-A2 PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-(2,3-f) QUINOLINE Wyeth (US) 2004-02-11 EP claimed
US-20030134222-A1 Photoresist composition and method of forming pattern using the same SAMSUNG ELECTRONICS CO., LTD. 2003-07-17 US claimed
US-20020187983-A1 Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline WYETH 2002-12-12 US claimed
WO-2002092602-A2 PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-[2,3-f] QUINOLINE WYETH (US) 2002-11-21 WO claimed
US-5476917-A Dispersity of pigments; gloss KOREA CHEMICAL CO., LTD. (KR) 1995-12-19 US claimed
US-4797425-A EPOXY RESIN FROM BISPHENOL WITH AMIDE HARDENERS TOTO LTD. (JP) 1989-01-10 US claimed
US-4245067-A EASILY HANDLED AND CURED AT NORMAL TEMPERATURE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-01-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020187983-A1 Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline CYP1A1, CYP2F1, CYP1B1 TDP1 1621/4885ALDH1A1 200/4885GLA 2728/4885
US-20040186123-A1 Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline CYP1A1, CYP2F1, CYP1B1 TDP1 1621/4885ALDH1A1 200/4885GLA 2728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.