Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997281 | 0.89 | NOTUM (0.39) | MAPTNOTUMNPSR1MEN1KMT2A | |
| SCHEMBL28997152 | 0.80 | NOTUM (0.40) | MAPK1P2RX7NOTUMMEN1KMT2A | |
| SCHEMBL28997288 | 0.78 | MEN1 (0.41) | NOTUMMEN1KMT2AALDH1A1 | |
| SCHEMBL28997292 | 0.75 | PTGER2 (0.40) | GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL28997140 | 0.75 | PTGER2 (0.39) | MAPTP2RX7NOTUMALDH1A1 | |
| SCHEMBL28997996 | 0.74 | CCR1 (0.40) | NOTUMALDH1A1 | |
| SCHEMBL28997289 | 0.72 | HSP90AA1 (0.35) | TSHRNPSR1KMT2A | |
| SCHEMBL30226142 | 0.72 | KDM4E (0.42) | GAATSHRMAPTP2RX7NOTUM | |
| SCHEMBL28997293 | 0.72 | KDM4E (0.42) | GAATSHRMAPTP2RX7NOTUM | |
| SCHEMBL28997299 | 0.72 | AR (0.44) | GAAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894323-A | Method for self-cyclizing cyanation of enaminoaniline compound | 湖北工业大学 | 2023-04-04 | — | — | CN | disclosed |