Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.40 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997244 | 1.00 | KRAS (0.46) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL26612388 | 0.83 | KRAS (0.58) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL26612396 | 0.83 | KRAS (0.58) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL28997431 | 0.82 | KRAS (0.53) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL28997427 | 0.82 | KRAS (0.53) | KRASSOS1VHLCDK7CCNH | |
| SCHEMBL28997444 | 0.82 | KRAS (0.41) | KRASSOS1 | |
| SCHEMBL30336327 | 0.82 | KRAS (0.41) | KRASSOS1 | |
| SCHEMBL28997446 | 0.82 | KRAS (0.41) | KRASSOS1 | |
| SCHEMBL26947438 | 0.81 | KRAS (0.53) | KRAS | |
| SCHEMBL22029274 | 0.81 | KRAS (0.60) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872979-A | Pyrimidine derivatives and their use in medicine | 广东东阳光药业有限公司 | 2023-03-31 | — | — | CN | disclosed |