Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997461 | 1.00 | SMARCA2 (0.41) | SMARCA2SMARCA4PBRM1TLR9GPR119 | |
| SCHEMBL30335662 | 1.00 | SMARCA2 (0.41) | SMARCA2SMARCA4PBRM1TLR9GPR119 | |
| SCHEMBL30826903 | 0.96 | SMARCA2 (0.41) | SMARCA2SMARCA4PBRM1TLR9GPR119 | |
| SCHEMBL28515676 | 0.96 | SMARCA2 (0.41) | SMARCA2SMARCA4PBRM1TLR9GPR119 | |
| SCHEMBL28515675 | 0.96 | SMARCA2 (0.41) | SMARCA2SMARCA4PBRM1TLR9GPR119 | |
| SCHEMBL25539655 | 0.90 | GPR119 (0.41) | SMARCA2SMARCA4PBRM1TLR9GPR119 | |
| SCHEMBL30335777 | 0.87 | TLR9 (0.38) | TLR9GPR119MAPTMEN1KMT2A | |
| SCHEMBL28998244 | 0.86 | SMO (0.37) | MAPTKCNH2KRAS | |
| SCHEMBL28998247 | 0.86 | SMO (0.37) | MAPTKCNH2KRAS | |
| SCHEMBL30335607 | 0.86 | GPR119 (0.38) | TLR9GPR119MEN1KMT2AKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872979-A | Pyrimidine derivatives and their use in medicine | 广东东阳光药业有限公司 | 2023-03-31 | — | — | CN | disclosed |