Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28996352 | 0.90 | KMT2A (0.35) | PDE2AKMT2A | |
| SCHEMBL29867704 | 0.66 | — | — | |
| SCHEMBL29563620 | 0.65 | TYK2 (0.38) | — | |
| SCHEMBL21329659 | 0.65 | TYK2 (0.38) | — | |
| SCHEMBL29562567 | 0.65 | TYK2 (0.38) | — | |
| SCHEMBL29562736 | 0.65 | TYK2 (0.38) | — | |
| SCHEMBL21329872 | 0.65 | TYK2 (0.38) | — | |
| SCHEMBL21329657 | 0.65 | TYK2 (0.38) | — | |
| SCHEMBL275728 | 0.64 | — | — | |
| SCHEMBL21330037 | 0.64 | CDK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907341-A | Pyridopyrimidinone derivatives, and preparation method and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-08-16 | — | — | CN | disclosed |
| WO-2022166974-A1 | PYRIDOPYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-08-11 | — | — | WO | disclosed |