Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28999844 | 0.85 | HPGD (0.64) | KMT2AALDH1A1POLBMAPTTDP1 | |
| SCHEMBL28999868 | 0.84 | ALDH1A1 (0.65) | KMT2AALDH1A1POLBMAPTTDP1 | |
| SCHEMBL108701 | 0.83 | KMT2A (0.73) | KMT2AALDH1A1POLBTDP1HPGD | |
| SCHEMBL28999825 | 0.81 | HSD17B10 (0.60) | KMT2AALDH1A1POLBTDP1KDM4E | |
| SCHEMBL28999824 | 0.80 | KDM4E (0.65) | KMT2AALDH1A1POLBTDP1KDM4E | |
| SCHEMBL28999849 | 0.80 | KMT2A (0.65) | KMT2AALDH1A1POLBMAPTTDP1 | |
| SCHEMBL28999828 | 0.80 | HPGD (0.61) | KMT2AALDH1A1POLBTDP1HPGD | |
| SCHEMBL28999865 | 0.79 | HSD17B10 (0.64) | KMT2AALDH1A1POLBTDP1KDM4E | |
| SCHEMBL28999827 | 0.78 | KMT2A (0.58) | KMT2AALDH1A1POLBTDP1HPGD | |
| SCHEMBL30259866 | 0.78 | HPGD (0.67) | KMT2AALDH1A1POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400573-B | Benzo [ d ] [1,3] dioxole compound, preparation method and application thereof | 中国人民解放军第二军医大学 | 2023-04-11 | — | — | CN | claimed |
| CN-109400573-B | Benzo [ d ] [1,3] dioxole compound, preparation method and application thereof | 中国人民解放军第二军医大学 | 2023-04-11 | — | — | CN | disclosed |