Biguanide

Biguanide

SCHEMBL29001087

CCOC(N)=O.N=C(N)NC(=N)N

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.68
GAA P10253 3/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
ALDH1A1 P00352 6/20 0.40
LMNA P02545 3/20 0.39
HSD17B10 Q99714 2/20 0.39
SOAT1 P35610 1/20 0.37
CHRM2 P08172 2/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
HTR1A P08908 1/20 0.35
TSHR P16473 1/20 0.35
CHRNB2 P17787 1/20 0.35
CYP2C19 P33261 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biguanide SCHEMBL29047761 0.98 ALOX15 (0.65) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL5392412 0.90 ALOX15 (0.60) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL4888567 0.85 ALOX15 (0.83) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL5392829 0.83 ALOX15 (0.79) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL1169096 0.83 ALOX15 (0.88) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL8136 0.83
Urethane SCHEMBL8505249 0.83 ALOX15 (1.00) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL367439 0.83 ALOX15 (1.00) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL8129017 0.83 ALOX15 (1.00) ALOX15GAAMGAMSIMGAM2
Urethane SCHEMBL8830978 0.83 ALOX15 (1.00) ALOX15GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118330099-A Extraction method and detection method of polyaminopropyl biguanide in cosmetics and raw materials 上海市食品药品检验研究院 2024-07-12 CN claimed
CN-118240323-A Antibacterial fiber sponge material and preparation method thereof 扬州中天海绵有限公司 2024-06-25 CN claimed
CN-118203522-A Sugar-resistant, oxidation-resistant and aging-resistant compound and preparation method and application thereof 上海肤徕生物高科技有限公司 2024-06-18 CN claimed
CN-118159244-A Lipid nanoparticle composition containing grape extract, cosmetic use of lipid nanoparticle composition containing grape extract, antioxidant skin cosmetic product and method for preventing skin aging and caring skin 艾奇实验室制药有限公司 2024-06-07 CN claimed
CN-118127816-A Antibacterial non-woven fabric and preparation method thereof 扬州亿诺无纺有限公司 2024-06-04 CN claimed
CN-118026263-A Method for preparing molybdenum hexafluoride with high conversion rate 浙江博瑞中硝科技有限公司 2024-05-14 CN claimed
CN-115606590-B Composite long-acting disinfectant and preparation method thereof 广州优尼康通卫生科技有限公司 2024-04-30 CN claimed
CN-117447034-B Sludge wrapping agent for recycling papermaking sludge and preparation method thereof 中聚达新材料(廊坊)有限公司 2024-04-05 CN claimed
CN-117721572-A Antistatic antibacterial plush fabric and preparation method thereof 安徽双盈纺织有限公司 2024-03-19 CN claimed
CN-117618614-A Deodorant and preparation method and application thereof 安徽坤健生物科技有限公司 2024-03-01 CN claimed
CN-116603007-A Wound surface disinfection spray and preparation method and application thereof 稳健医疗用品股份有限公司 2023-08-18 CN claimed
CN-116549307-A Nerve-soothing and soothing type eye and lip cleansing lotion and preparation method thereof 杭州心悦化妆品有限公司 2023-08-08 CN claimed
CN-116530520-A Composite disinfectant with excellent effect and preparation method thereof 上海腾灵建设集团有限公司 2023-08-04 CN claimed
CN-113648242-B Mild type anti-corrosion system and preparation method and application thereof 湖北神农芳香大健康产业有限公司 2023-07-25 CN claimed
CN-116349673-A Compound disinfectant containing plant antibacterial essential oil and preparation method thereof 以岭健康科技有限公司 2023-06-30 CN claimed
CN-115399315-B Fresh flower preservative and preparation method thereof 凡美(广州)农业科技有限公司 2023-06-16 CN claimed
CN-116200229-A Chitosan oligosaccharide-containing deproteinized contact lens care solution 上海应用技术大学 2023-06-02 CN claimed
CN-116139043-A Cleansing water and preparation method thereof 广州世航生物科技有限公司 2023-05-23 CN claimed
CN-116077395-A Infant lip balm and preparation method thereof 江苏爱舒屋化妆品有限公司 2023-05-09 CN claimed
CN-113291017-B Waterproof coiled material with antibacterial function and application 北京东方雨虹防水技术股份有限公司 2023-05-02 CN claimed