Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001666 | 1.00 | HCAR3 (0.61) | HCAR3KMT2ATSHRHTTMEN1 | |
| SCHEMBL28935448 | 0.97 | HCAR3 (0.65) | HCAR3KMT2ATSHRHTTMEN1 | |
| SCHEMBL28935447 | 0.97 | HCAR3 (0.65) | HCAR3KMT2ATSHRHTTMEN1 | |
| SCHEMBL28939260 | 0.97 | HCAR3 (0.65) | HCAR3KMT2ATSHRHTTMEN1 | |
| SCHEMBL20266402 | 0.94 | HCAR3 (0.56) | HCAR3KMT2ATSHRHTTMEN1 | |
| SCHEMBL20266401 | 0.94 | HCAR3 (0.56) | HCAR3KMT2ATSHRHTTMEN1 | |
| SCHEMBL24900139 | 0.88 | KMT2A (0.51) | HCAR3KMT2ATSHRHTTMEN1 | |
| SCHEMBL24900222 | 0.84 | KMT2A (0.55) | HCAR3KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL24900028 | 0.84 | KMT2A (0.55) | HCAR3KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL23286797 | 0.84 | KMT2A (0.55) | HCAR3KMT2ATSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102543-A | GLP-1R agonist, synthesis method and application thereof | 江南大学 | 2023-05-12 | — | — | CN | disclosed |