⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL1146592 | 0.91 | — | — | |
| Methyl Alcohol SCHEMBL27906542 | 0.83 | — | — | |
| Methyl Alcohol SCHEMBL5475923 | 0.82 | — | — | |
| Hydroxyamine SCHEMBL346278 | 0.82 | — | — | |
| Methyl Alcohol SCHEMBL1944970 | 0.82 | — | — | |
| Methyl Alcohol SCHEMBL25433773 | 0.73 | — | — | |
| Hydroxyamine SCHEMBL7997982 | 0.73 | — | — | |
| Methyl Alcohol SCHEMBL1100064 | 0.73 | — | — | |
| Ethane SCHEMBL1973570 | 0.73 | — | — | |
| Methyl Alcohol SCHEMBL11522005 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114539098-B | Difunctional HDAC6 inhibitor, synthesis method and application | 青岛大学 | 2024-05-24 | — | — | CN | claimed |
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | claimed |
| CN-116655577-B | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-11-14 | — | — | CN | claimed |
| CN-116655577-A | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-08-29 | — | — | CN | claimed |
| CN-114181116-B | D-amino acid derivative aminopeptidase N inhibitor, and preparation method and application thereof | 山东中医药大学 | 2023-05-23 | — | — | CN | claimed |
| CN-114539098-B | Difunctional HDAC6 inhibitor, synthesis method and application | 青岛大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-113582911-B | Multi-target donepezil-hydroxamic acid compound, and preparation method and application thereof | 山东大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115232130-B | APN and AKT double-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-113754591-B | HDAC, JAK and BET three-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-116655577-B | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-116655577-A | Flavone derivative aminopeptidase N inhibitor and preparation method and application thereof | 山东中医药大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-114181116-B | D-amino acid derivative aminopeptidase N inhibitor, and preparation method and application thereof | 山东中医药大学 | 2023-05-23 | — | — | CN | disclosed |