Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003194 | 1.00 | BTK (0.44) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL29003323 | 1.00 | BTK (0.44) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL28687366 | 0.90 | BTK (0.48) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL28708704 | 0.87 | DRD2 (0.45) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL28495723 | 0.87 | DRD2 (0.45) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL23070671 | 0.85 | BTK (0.47) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL29003197 | 0.85 | BTK (0.47) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL29003211 | 0.85 | BTK (0.47) | BTKKMT2AL3MBTL1KAT8CTSK | |
| SCHEMBL20233119 | 0.84 | BTK (0.51) | BTKKMT2AL3MBTL1CTSKGAA | |
| SCHEMBL12424476 | 0.84 | BTK (0.51) | BTKKMT2AL3MBTL1CTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157388-A | Carbocyclic amide derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-05-23 | — | — | CN | disclosed |