Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353317 | 1.00 | DRD2 (0.46) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL1353315 | 1.00 | DRD2 (0.46) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL28426812 | 0.91 | BTK (0.50) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL29470586 | 0.91 | BTK (0.50) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL12911093 | 0.87 | DRD2 (0.50) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL12688495 | 0.87 | DRD2 (0.50) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL12688427 | 0.87 | DRD2 (0.50) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL31643918 | 0.87 | DRD2 (0.46) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL5009901 | 0.87 | DRD2 (0.46) | DRD2BTKEPHX1KDM1AMAOB | |
| SCHEMBL31644688 | 0.87 | DRD2 (0.47) | DRD2BTKEPHX1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157388-A | Carbocyclic amide derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022053000-A1 | CARBOCYCLIC AMIDE DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2022-03-17 | — | — | WO | disclosed |