Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003175 | 1.00 | PIK3CD (0.36) | PIK3CDATRKMT2AL3MBTL1RXRA | |
| SCHEMBL29003183 | 1.00 | PIK3CD (0.36) | PIK3CDATRKMT2AL3MBTL1RXRA | |
| SCHEMBL29003218 | 0.95 | PIK3CD (0.38) | PIK3CDATRKMT2AL3MBTL1RXRA | |
| SCHEMBL29003158 | 0.93 | CACNB4 (0.37) | PIK3CDATRKMT2AL3MBTL1RXRA | |
| SCHEMBL29003157 | 0.93 | CACNB4 (0.37) | PIK3CDATRKMT2AL3MBTL1RXRA | |
| SCHEMBL29003441 | 0.93 | CACNB4 (0.37) | PIK3CDATRKMT2AL3MBTL1RXRA | |
| SCHEMBL29003393 | 0.87 | ATR (0.39) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003212 | 0.87 | ATR (0.39) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003209 | 0.87 | ATR (0.39) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL30424835 | 0.87 | ATR (0.39) | ATRKMT2AL3MBTL1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157388-A | Carbocyclic amide derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022053000-A1 | CARBOCYCLIC AMIDE DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2022-03-17 | — | — | WO | disclosed |