Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 6/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003393 | 1.00 | ATR (0.39) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003212 | 1.00 | ATR (0.39) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL30424835 | 1.00 | ATR (0.39) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL30869077 | 0.93 | ATR (0.40) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003273 | 0.87 | PIK3CD (0.36) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003175 | 0.87 | PIK3CD (0.36) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003183 | 0.87 | PIK3CD (0.36) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003294 | 0.87 | ATR (0.40) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003281 | 0.87 | ATR (0.40) | ATRKMT2AL3MBTL1RXRARXRB | |
| SCHEMBL29003348 | 0.87 | ATR (0.40) | ATRKMT2AL3MBTL1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157388-A | Carbocyclic amide derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022053000-A1 | CARBOCYCLIC AMIDE DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 四川海思科制药有限公司 | 2022-03-17 | — | — | WO | disclosed |