Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.64 |
| ▸ | ACR | P10323 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | RXRB | P28702 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396251 | 0.93 | MAPT (0.83) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL14062435 | 0.93 | MAPT (0.83) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL1790578 | 0.88 | MAPT (0.87) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL2395069 | 0.88 | MAPT (0.75) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL14062417 | 0.88 | MAPT (0.75) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL8210174 | 0.88 | MAPT (1.00) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL14062466 | 0.88 | MAPT (0.75) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL21266478 | 0.86 | MAPT (0.73) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL16775315 | 0.86 | MAPT (0.73) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL4328066 | 0.86 | MAPT (0.73) | MAPTTDP1L3MBTL1PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956976-A | Novel indenofluorene-6, 12-diketone derivative and synthetic method and application thereof | 商丘师范学院 | 2022-08-30 | — | — | CN | disclosed |