⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623413 | 0.76 | — | — | |
| SCHEMBL18952873 | 0.72 | KDM4E (0.37) | — | |
| SCHEMBL5182903 | 0.70 | — | — | |
| SCHEMBL16837122 | 0.70 | PIK3CD (0.32) | — | |
| SCHEMBL14920897 | 0.69 | — | — | |
| SCHEMBL3565028 | 0.69 | — | — | |
| SCHEMBL10677727 | 0.67 | ENPP1 (0.40) | — | |
| SCHEMBL1586085 | 0.65 | — | — | |
| SCHEMBL4500209 | 0.65 | ENPP3 (0.32) | — | |
| SCHEMBL17654330 | 0.64 | CYP3A4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |