Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.46 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.38 |
| ▸ | KDM6B | O15054 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 3/20 | 0.38 |
| ▸ | KDM5C | P41229 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29005368 | 0.99 | SYK (0.46) | SYKCAMKK1CAMKK2BRD4CDK9 | |
| SCHEMBL30445973 | 0.98 | SYK (0.46) | SYKCAMKK1CAMKK2BRD4CDK9 | |
| SCHEMBL30446102 | 0.98 | SYK (0.46) | SYKCAMKK1CAMKK2BRD4CDK9 | |
| Ammonia Solution, Strong SCHEMBL29005335 | 0.86 | CDK4 (0.50) | SYKMAP4K1CDK2 | |
| Ammonia Solution, Strong SCHEMBL29005328 | 0.85 | CDK4 (0.49) | SYKMAP4K1CDK2 | |
| SCHEMBL30445224 | 0.84 | CDK4 (0.50) | SYKMAP4K1CDK2 | |
| SCHEMBL30445681 | 0.83 | CDK4 (0.49) | SYKMAP4K1CDK2 | |
| Ammonia Solution, Strong SCHEMBL29005340 | 0.82 | CDK9 (0.46) | SYKCAMKK2BRD4CDK9CDK2 | |
| SCHEMBL30445546 | 0.81 | CDK9 (0.46) | SYKCAMKK2BRD4CDK9CDK2 | |
| SCHEMBL28673278 | 0.78 | HDAC1 (0.60) | BRD4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999210-B | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2023-05-23 | — | — | CN | claimed |
| CN-113999210-B | Group of 2-phenylamino-4-triazolyl pyrimidine derivatives and application thereof | 郑州大学第一附属医院 | 2023-05-23 | — | — | CN | disclosed |